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Dermal Drug Delivery
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At Aptar Pharma, we understand your challenges in dermal drug delivery and turn them into opportunities for you.

We offer a broad range of versatile dispensing solutions, leveraging our human factor and digital healthcare capabilities, to strengthen your brand presence.

We provide expertise in regulatory support and technical guidance to accelerate and derisk your path to market while ensuring product quality, compliance and sustainability.

Aptar Pharma is more than just a supplier - we are your preferred drug delivery partner for developing your dermal combination products all the way from formulation to patient.

Your Partner in Dermal Drug Delivery Solutions

 

With decades of experience in the design and manufacture of a portfolio of dermal drug delivery systems, Aptar Pharma offers products with a unique combination of dermal dispensing features backed with extensive regulatory and technical expertise that can accelerate and derisk the development of drug device combination products.

Applying medication to the skin can require precise and reliable dosing from a dispensing system that also protects the liquid, gel, cream or lotion formulation from external contamination or conditions.

From topical applications applied directly to the skin or dermal systemic indications, dermal drug delivery can offer numerous advantages through the use of Aptar Pharma’s advanced dermal drug delivery systems and support services.

Range of dermal drug delivery systems including spray pumps, airless dispensers, and child-resistant packaging formats for different applications.

Flexibility to Dermal Drug Markets

 

We provide the flexibility you need to support and widen your dermal drug delivery product portfolio.

With an extensive history of success in the dermal segment, Aptar Pharma truly understands the needs of dermal drug manufacturers and product users from markets with varying levels of regulation.

Our broad portfolio of dermal drug delivery solutions can meet the varying requirements of a range of formulations, products and patient needs.

Aptar Pharma can also provide custom solutions for your next innovative product covering prescription innovator, OTC consumer or generic product applications.

User applying a dermal formulation using a spray pump onto the elbow, illustrating delivery of liquid or semi-solid formulations to the skin.

Range of Dermal Formulation Types

 

Our portfolio of dermal drug dispensing solutions can support a broad range of galenic forms, including liquid and semi-solid formulations for dermal and topical applications.

  • Airless+ systems can dispense formulations covering a wide range of viscosities, from lotions to creams, in a sealed system protected from light and air.
  • Spray Pumps represented by APFPlus, Classic Line and VP6 pump technologies can deliver formulations with a range of viscosities to the skin.
  • Bag-On-Valve (BOV) is compatible with a broad range of liquid to semi-solid formulations including gels and creams.

User applying a dermal formulation to the knee using an airless dispensing system for targeted topical or transdermal application.

Growing Therapeutic Dermal Applications

 

Aptar Pharma manufactures and supplies a portfolio of dermal drug delivery technologies that are suitable for a range of therapeutic applications.

From topical skin treatments to transdermal pain relief, advanced wound care or hormone treatments, Aptar Pharma’s dermal drug delivery technologies have been widely used in many different dermal drug applications.

Technical illustration of a spray pump with tip seal mechanism showing closed and open positions to prevent contamination through the orifice.

Hygienic Dermal Product Protection

 

Our dermal drug delivery systems offer clean and hygienic dispensing combined with robust product protection.

  • Airless+ semi-solid dispensing systems protect sensitive formulations from air and light.
  • Aptar’s BOV system separates the formulation from the propellant thanks to its multi-layer bag, providing a high level of barrier protection against diffusion while helping protect sensitive formulations.
  • APFPlus Top Seal technology uses a spring-loaded mechanism to close the spray orifice after each actuation, helping to protect preservative-free formulations from contamination and prevent nozzle clogging.

The illustration of the dermal dispensing spray pump with 360-degree functionality

Innovative Dermal Dispensing

 

Aptar Pharma has developed high-quality and innovative dermal drug delivery systems that can be customized to individual needs.

For some solutions, customized options such as color, printing, and more are available to help you support your unique brand presence.

Collage of dermal application areas including face, shoulder, and hands, illustrating different types of topical and dermal treatment uses.

Versatile Solutions for Dermal Formulations

 

Aptar Pharma’s dermal drug delivery solutions are designed to meet the performance requirements demanded by a range of today’s formulation viscosities, galenic forms or device technologies.

Our portfolio of dermal delivery systems can dispense a wide range of formulation viscosities, supporting the requirements of most applications.

We Have a Broad Range of Value Added Services to Accelerate and Derisk Your Drug Product Development.

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Recently Published Resources

10 Jun 2025
Topical Dermal Drug Delivery System Innovation and Sustainability

Pharmaceutical Publications
20 Dec 2024
Bringing Topical Drugs to Patients’ Skin: Managing the Drug Delivery Ecosystem

Pharmaceutical Webinars
06 Jul 2023
Case Study – The Airless+ Dermal Drug Delivery System

Pharmaceutical Case Studies
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De-Risking Combination Product Registration for Semi-Solids with Aptar Pharma Airless+ Systems

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